Haemochromatosis is a hereditary disease marked by improper dietary iron metabolism. This disease causes the presence of iron in different body tissues. This iron accumulation causes organ damage usually in liver and pancreas. Resulting liver failure and develops diabetes mellitus. According to different survey reports it has been found that about one in every 300-400 people develop this syndrome which is more common in northern Europe and especially in people belonging from England, Ireland, Scotland and Wales.
Haemochromatosis is the concept of hereditary hemochromatosis where some genetic mutations inclination causes iron accumulation. The disease is usually caused by
iron overload usually in genetic causes. The disease was first described in the year 1865 by Armand Trousseau.
Signs and Symptoms of Haemochromatosis
The disease is a very difficult detect as the symptoms are not that frequent. It often presents with the symptoms that are often found in other disease also. In many cases people having hereditary Haemochromatosis never show any symptoms of iron accumulation. The common symptoms of the disease include the following:
- Liver cirrhosis which is often followed with painfully enlarged liver.
- Another symptom is Malaise
- Erectile dysfunction and hypogonadism
- Insulin resistance which causes from pancreatic damage from iron precipitation.
- Decreased libido
- Erectile dysfunction as well as hypogonadism
- Hearing impairment
- Arthritis in the body joints like hands, knee and shoulder joints
- Dyskinesias, which includes Parkinsonian symptoms
- Heart failure, arrhythmias or pericarditis
- Dyskinesias, supported by Parkinsonian symptoms
- Adrenal gland
- Pancreatic gland
- Parathyroid gland
- Testes or ovary
- Pituitary gland
- Dark skin color
- Being prone to some infectious diseases which develop due to siderophilic microorganisms
The Haemochromatosis is usually common in males in fifties and women develop it in the age of sixties. The early symptoms include Stiff joints, diabetes, and fatigue. Diagnosis of Haemochromatosis is often difficult as clinically the disease has very less traces.
The diagnosis involves treatment of organ damage, stopping the intake of alcoholic beverages, vitamin c, red meat and other immediate causes of having food poisoning. The diagnosis also involves increasing the intake of substances that reduce the iron absorption like high-tannin tea, calcium, and foods containing oxalic and phytic acids.
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